The liver is one of the most important organ that plays a vital role in regulating the metabolic activities of the body and detoxifying the body by filtering out toxic and harmful chemicals. Liver Function Test (LFT) is a blood test that provide useful information about the wellness of the liver. It measures the levels of proteins, liver enzymes, and bilirubin in your blood. LFT test comprises of certain parameters like Albumin Test, Bilirubin Test, SGOT, SGPT, and more.
A liver function test can be performed for many reasons. Some physicians perform LFT as a part of a routine check-up, while some physicians may recommend a liver function test to screen patients who are at the risk of developing liver diseases. LFT is also used to monitor an individual’s liver disease and to see the effectiveness of treatment.
A liver function test is usually recommended in the following conditions:
LFT is used to determine the level of enzymes and proteins in the blood. Higher or lower levels with respect to normal may be an indication of liver disease. Some common LFT’s are:
Aspartate transaminase (AST) – AST is an enzyme that metabolizes amino acids. AST is usually present in the bloodstream in a low amount. An increased level of AST is an indication of liver damage.
Alkaline phosphatase (ALP) – ALP is an enzyme that is present in the liver and bones, and it is important in the breaking down of proteins. An increased level of ALP indicates liver diseases, such as blocked bile duct or few bone diseases.
Gamma-glutamyl transferase (GGT) – An enzyme found in a large amount in the liver, bile ducts, and pancreas. An increased level of GGT can be a sign of liver or bile duct damage.
The total protein is the amount of protein present in your blood. Two main proteins found in blood are albumin and globulins.
Globulin – It is a protein found in the liver and it helps the immune system to fight against infections. Decreased levels of globulin can be a sign of liver damage.
Albumin – Another protein in the liver is albumin. An albumin test measures how well the liver is making proteins that the human body requires. Low albumin may be an indication of liver damage.
Prothrombin (PT) – Prothrombin is a protein found in the liver and is responsible for blood clotting. A prothrombin test evaluates how much time it takes for the blood to clot.
Bilirubin is a yellowish fluid made in the body when the red blood cells break down. This test measures the bilirubin level in the body. If the liver is damaged, bilirubin can leak out of the liver into the blood. This is one of the major causes of jaundice.
The liver function test helps determine the liver’s health. The liver is responsible for numerous vital functions of the body, such as:
Symptoms for an unhealthy liver include:
Liver problems can make a person sick and can be life-threatening. Please consult your physician for further opinion.
Few food items and medications may affect the levels of enzymes and proteins in the blood. Doctors may advise the patients to avoid some food items and medicines before the test.
During Liver Function Test, blood is drawn from a vein, usually from the arm region, and then tested in the pathology laboratory.
Blood drawn is a part of a routine protocol and rarely cause any side effect. But there may be some minor risks of giving blood samples. These includes:
Standard blood test for LFT includes the following parameters:
Test Name |
Reference Range |
ALT |
7-55 U/L |
AST |
8-48 U/L |
ALP |
40-129 U/L |
Total Protein |
6.3-7.9 g/dL |
Albumin |
3.5-5 g/dL |
Bilirubin |
0.1-1.2 mg/dL |
GGT |
8-60 U/L |
PT |
9-13 seconds |
Diagnostic and Pathology Tests Available At House of Diagnostics (HOD).
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